Music Interventions in Anxiety and Pain Management in Patients Undergoing Total Knee and Hip Arthroplasty
DOI:
https://doi.org/10.65150/EP-jsshrs/V2E6/2026-08Keywords:
music intervention, total knee arthroplasty, total hip arthroplasty, preoperative anxiety, narrative reviewAbstract
Background: Preoperative anxiety and postoperative pain represent two prominent clinical challenges in patients undergoing total knee arthroplasty (TKA) and total hip arthroplasty (THA). Music interventions, encompassing passive music listening and therapist-guided music therapy, are attracting growing interest as safe, low-cost non-pharmacological options within perioperative opioid-minimization strategies.
Objectives: To synthesize and critically appraise scientific evidence from 2020 to 2025 on the effectiveness of music interventions for anxiety and pain in arthroplasty patients; to clarify proposed neurobiological mechanisms; to identify moderating factors of outcomes; and to discuss clinical implications and priority research directions.
Methods: A narrative review with transparent search, conducted in accordance with SANRA guidelines, was performed. This approach was selected to enable critical synthesis and conceptual integration across diverse study designs, including randomized controlled trials (RCTs), systematic reviews, and mechanistic studies, rather than providing a quantitative pooled estimate. Purposive searches were conducted across five electronic databases for the period 2020 to 2025. Evidence was stratified according to its degree of directness to the TKA/THA population: core evidence from studies conducted specifically in orthopaedics and joint arthroplasty; contextual evidence from multispecialty perioperative meta-analyses; and mechanistic evidence from neurobiological research.
Main Results: Evidence suggests that music interventions are associated with reductions in preoperative anxiety and postoperative pain of small to moderate effect size in orthopaedic populations (standardized mean difference [SMD] approximately -0.27 to -0.40; a negative SMD denotes reduction in the intervention group relative to the control group). One TKA-specific meta-analysis found no statistically significant reduction in pain Visual Analogue Scale (VAS) scores, yet documented significant shift in autonomic nervous system balance. Contextual evidence from multispecialty meta-analyses yielded larger effect sizes (SMD approximately -0.90) that cannot be directly extrapolated to TKA/THA. Evidence regarding prevention of postoperative delirium remains indirect.
Conclusions: Current evidence suggests that music interventions may confer clinical benefit in perioperative management of joint arthroplasty. However, TKA/THA-specific evidence remains more limited than that available for broader surgical populations and requires reinforcement by adequately powered, multicenter randomized controlled trials.
References
1) Abate, S. M., Chekol, Y. A., & Basu, B. (2020). Global prevalence and determinants of preoperative anxiety among surgical patients: A systematic review and meta-analysis. International Journal of Surgery Open, 25, 6-16. https://doi.org/10.1016/j.ijso.2020.05.010
2) Aguero-Millan, B., Abajas-Bustillo, R., & Ortego-Mate, C. (2023). Efficacy of nonpharmacologic interventions in preoperative anxiety: A systematic review of systematic reviews. Journal of Clinical Nursing, 32(17-18), 6229-6242.
3) Arnold, C. A., Bagg, M. K., & Harvey, A. R. (2024). The psychophysiology of music-based interventions and the experience of pain. Frontiers in Psychology, 15, Article 1361857. https://doi.org/10.3389/fpsyg.2024.1361857
4) Baethge, C., Goldbeck-Wood, S., & Mertens, S. (2019). SANRA: A scale for the quality assessment of narrative review articles. Research Integrity and Peer Review, 4, Article 5. https://doi.org/10.1186/s41073-019-0064-8
5) Brown, A., Muench, J., & Steen, D. (2024). The effect of music on postoperative agitation, pain, and opioid use among patients undergoing total knee replacement. Pain Management Nursing, 25(4), e2-e8. https://doi.org/10.1016/j.pmn.2024.04.009
6) Chiang, B., Marquardt, C., Martin, J. C., Malyavko, A., & Tabaie, S. (2022). The role of music-based interventions in orthopaedic surgery. Cureus, 14(11), Article e31157. https://doi.org/10.7759/cureus.31157
7) Tran, B. W., Nowrouz, M. Y., Dhillon, S. K., Xie, K. K., Breslin, K. M., & Golladay, G. J. (2020). The impact of music and noise cancellation on sedation requirements during total knee replacement: A randomized controlled trial. Geriatric Orthopaedic Surgery & Rehabilitation, 11, 2151459320910844. https://doi.org/10.1177/2151459320910844
8) Ginsberg, J. P., Raghunathan, K., Bassi, G., & Ulloa, L. (2022). Review of perioperative music medicine: Mechanisms of pain and stress reduction around surgery. Frontiers in Medicine, 9, Article 821022. https://doi.org/10.3389/fmed.2022.821022
9) Goel, S. K., Kim, V., Kearns, J., Gilden, D., Bowers, C., Brown, T., & Donahue, K. (2024). Music-based therapy for the treatment of perioperative anxiety and pain: A randomized, prospective clinical trial. Journal of Clinical Medicine, 13(20), Article 6139. https://doi.org/10.3390/jcm13206139
10) Kuhlmann, A. Y. R., de Rooij, A., Kroese, L. F., van Dijk, M., Hunink, M. G. M., & Jeekel, J. (2018). Meta-analysis evaluating music interventions for anxiety and pain in surgery. British Journal of Surgery, 105(7), 773-783. https://doi.org/10.1002/bjs.10853
11) Li, G., Yu, L., Yang, Y., Deng, J., Shao, L., & Zeng, C. (2024). Effects of perioperative music therapy on patients with postoperative pain and anxiety: A systematic review and meta-analysis. Journal of Integrative and Complementary Medicine, 30(1), 37-46. https://doi.org/10.1089/jicm.2022.0803
12) Lin, C., Hwang, S., Jiang, P., & Hsiung, N. H. (2020). Effect of music therapy on pain after orthopedic surgery: A systematic review and meta-analysis. Pain Practice, 20(4), 422-436. https://doi.org/10.1111/papr.12864
13) Park, S., Lee, S., Howard, S., & Yi, J. (2024). Technology-based music interventions to reduce anxiety and pain among patients undergoing surgery or procedures: Systematic review of the literature. JMIR mHealth and uHealth, 12, Article e48802. https://doi.org/10.2196/48802
14) Patiyal, N., Kalyani, V., Mishra, R., Kataria, N., Sharma, S., Parashar, A., & Kumari, P. (2021). Effect of music therapy on pain, anxiety, and use of opioids among patients underwent orthopedic surgery: A systematic review and meta-analysis. Cureus, 13(9), Article e18377. https://doi.org/10.7759/cureus.18377
15) Poulsen, M. J., Coto, J., & Cooney, M. F. (2021). The effects of music intervention on pain and anxiety in the immediate postoperative period in adults undergoing total knee arthroplasty and total hip arthroplasty. Journal of PeriAnesthesia Nursing, 36(5), 467-473.
16) Ran, R., Ying, Y., & Zhang, W. (2023). Five-element music stimulation in the perioperative period: Improvement of pain and anxiety in orthopedic surgery patients. Actas Espanolas de Psiquiatria, 51(6), 250-261.
https://doi.org/10.51338/rppsiquiatria2023.v51.i6.pp250-261
17) Rohden, G. B., Prietsch, V., Fernandes, A. L., Garcia, A. M. C., & Tarter, S. (2024). The effectiveness of music therapy in reducing perioperative pain and anxiety: A systematic review of randomized controlled trials. Perioperative Care and Operating Room Management, 34, Article 100367.
18) Sorel, J. C., Overvliet, G. M., Gademan, M. G. J., den Haan, C., Honig, A., & Poolman, R. W. (2020). The influence of perioperative interventions targeting psychological distress on clinical outcome after total knee arthroplasty. Rheumatology International, 40(12), 1961-1986. https://doi.org/10.1007/s00296-020-04644-y
19) Van Bergen, S. H., Verhoeven, J. G., Kakar, E., Jeekel, J., Birnie, E., & Klimek, M. (2025). Implementation of music in the perioperative standard care of colorectal surgery: A cost-effectiveness analysis. Journal of Surgical Research, 305, 47-55.
20) Yu, R., Zhuo, Y., Feng, E., Wang, W., Lin, W., Lin, F., Li, Z., Lin, L., Xiao, L., Wang, H., Huang, Y., Wu, C., & Zhang, Y. (2020). The effect of musical interventions in improving short-term pain outcomes following total knee replacement: A meta-analysis and systematic review. Journal of Orthopaedic Surgery and Research, 15(1), Article 465. https://doi.org/10.1186/s13018-020-01995-x
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Copyright (c) 2026 Trần Thị Thu Trang, Nguyen Thuy Van, Dinh Thi Thanh Huyen, Nguyen Thi Hao, Hoang Thi Thu Ha, Pham Hoang Giang, Nguyen Thi To Uyen (Author)

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